PhaseFolio

Biotech rNPV / probability-of-success engine for AI agents.

CommunityOnlineNo sign-inGlobalFreeCan modify data

What it can do

  • Get Project: Fetch a PhaseFolio project's metadata: indication, sub-indication, modality, biomarker, asset name, and stage at entry. Use this when you need to ground an analysis question in the projec
  • List Scenarios: List all scenarios in a PhaseFolio project. Returns scenario IDs, names, created/updated timestamps, and top-line eNPV/rNPV. Use this to discover what scenarios exist before fetching o
  • Get Scenario: Fetch a PhaseFolio scenario's complete inputs (stage costs, durations, PoS, commercial assumptions, IRA settings) and computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, t

What data it sees

Do you need an account

No: the server works without sign-in

Biotech rNPV / probability-of-success engine for AI agents. Audit-grade asset valuation with signed dossier exports, cell-level evidence registers, and asset-anchored competitive landscape — the same engine healthcare investors and tech transfer offices use to value early-stage biotech assets, exposed directly to your AI analyst.

Tools

Public tier — no auth required

  • query_benchmarks — anonymized network statistics (PoS by indication × modality, cost / duration percentiles)
  • verify_export — verify a signed PhaseFolio dossier by content hash or URL; returns issued timestamp, methodology version, originating-org identifier
  • get_methodology — fetch any methodology section in citable form (backtest, PoS calibration, IRA framework, evidence standards, network benchmarks)

Bearer tier — request a token at app.phasefolio.com/contact

  • get_project — project metadata: indication, sub-indication, modality, biomarker, asset name, stage at entry
  • list_scenarios — scenarios in a project with top-line eNPV / rNPV
  • get_scenario — full scenario inputs + computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, top sensitivity drivers)
  • get_evidence — evidence-register entries: citations, sources, supporting documents, freshness
  • get_dossier — structured dossier JSON, mirroring the IC Dossier PDF / Excel exports
  • query_landscape — asset-anchored competitive landscape (comparable trials, competing programs, sponsor activity, biomarker overlap) sourced from CT.gov + FDA + curated enrichment

Trust artifacts

Every PhaseFolio dossier export carries a cryptographic signature tying file content to engine version and methodology version. AI agents can verify any artifact in one tool call. Public key at /.well-known/phasefolio-pubkey.pem.

Methodology is fully published and citation-ready at app.phasefolio.com/methodology. Backtested on a held-out cohort: 16 rheumatoid-arthritis programs, AUC 0.625, Wilson 95% CI on accuracy. Oncology backtest in progress.

Sources

How to connect

How to connect PhaseFolio to Claude

The server address to paste into Claude settings:

https://phasefolio.run.tools

  1. Open Claude (claude.ai or the desktop app).
  2. Go to Settings → Connectors.
  3. Click Add custom connector.
  4. Paste the server address copied below into Remote MCP server URL and click Add.
  5. In a chat, click + → Connectors and switch the new connector on.

Custom connectors are available on Free, Pro, Max, Team and Enterprise plans (Free is limited to one). On Team and Enterprise an organization Owner adds the connector first under Organization settings → Connectors.

Authorization

After you click Add, a sign-in window for the service opens. Sign in with your own account and approve access. Claude never sees your password.

How to connect PhaseFolio to ChatGPT

The server address to paste into ChatGPT settings:

https://phasefolio.run.tools

  1. Open ChatGPT in a browser (chatgpt.com). A Plus, Pro, Business, Enterprise or Edu plan is required.
  2. Turn on developer mode once: Settings → Apps → Advanced settings → Developer mode.
  3. Open Settings → Connectors and click Create.
  4. Fill in the form: Name (anything), Description (one line about what the service does), MCP server URL (copy it below).
  5. Under Authentication choose OAuth if the service requires sign-in, otherwise None. Click Create.
  6. In a new chat open + → Apps/Connectors and enable the connector.

OpenAI has renamed this section before (Connectors → Apps/Plugins). If the label differs, search settings for "developer mode". On Business/Enterprise workspaces an admin must allow custom connectors first.

Authorization

On first use ChatGPT opens the service's sign-in window. Sign in and approve access.

How to connect PhaseFolio to Cursor

The server address to paste into Cursor settings:

https://phasefolio.run.tools

Fastest: click Open in Cursor below and confirm the prompt.

Manually:

  1. In Cursor open Settings → Cursor Settings → MCP and click Add new global MCP server.
  2. Paste the JSON copied below into ~/.cursor/mcp.json (per project: .cursor/mcp.json in the repo root).
  3. Save the file. The server appears in the MCP list; authorize it there if asked.

Authorization

If the service needs sign-in, an authorize button appears next to the server in the MCP list.

Server tool list (9)

Raw names from tools/list. Only developers need these.

get_projectFetch a PhaseFolio project's metadata: indication, sub-indication, modality, biomarker, asset name, and stage at entry. Use this when you need to ground an analysis question in the project's clinical context before fetching scenarios.
list_scenariosList all scenarios in a PhaseFolio project. Returns scenario IDs, names, created/updated timestamps, and top-line eNPV/rNPV. Use this to discover what scenarios exist before fetching one in detail.
get_scenarioFetch a PhaseFolio scenario's complete inputs (stage costs, durations, PoS, commercial assumptions, IRA settings) and computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, top sensitivity drivers). This is the authoritative engine output — every signed export ties back to this payload.
get_evidenceFetch the evidence register entries for a scenario — the citations, sources, and supporting documents the analyst attached to back the assumptions. Use this when an analysis question references 'what's the evidence for X?'
get_dossierFetch the structured dossier JSON for a scenario — the same content rendered in the IC Dossier PDF/Excel exports, in machine-readable form. Includes verdict, drivers, assumptions, evidence summary, and (if available) signed-export hashes pointing to the latest signed artifacts.
query_landscapeFetch the asset-anchored competitive landscape for a project — comparable trials, competing programs, sponsor activity, and biomarker overlap. Sourced from CT.gov + FDA + PhaseFolio's curated enrichment. Use when an analysis question asks 'who else is working on this?' or 'what's the competitive context?'
query_benchmarksQuery PhaseFolio's network benchmarks — anonymized aggregate statistics across the network of scenarios (PoS by indication × modality, cost distributions, duration percentiles). L1 tier (no auth) returns lagged, low-granularity headlines; L3 tier (bearer auth) returns granular slices with biomarker stratification.
verify_exportVerify a signed PhaseFolio export. Accepts either a content hash (from a signed PDF/Excel) or a URL to a hosted artifact. Returns verification status (valid/tampered/unknown), issued timestamp, methodology version, and an anonymized originating-org identifier. Use this when a user shares a PhaseFolio dossier and you want to confirm it's authentic before citing the analysis.
get_methodologyFetch a PhaseFolio methodology section's full content (backtest, PoS calibration, IRA framework, evidence standards, network benchmarks, COGS benchmark, SG&A benchmark, tax benchmark). Designed for citation: each section has a stable URL and a methodology version identifier you can reference in analysis output.