PhaseFolio

Biotech rNPV / probability-of-success engine for AI agents.

CommunityOnlineNo sign-inGlobalFreeCan modify data

What it can do

  • Get Project: Fetch a PhaseFolio project's metadata: indication, sub-indication, modality, biomarker, asset name, and stage at entry. Use this when you need to ground an analysis question in the projec
  • List Scenarios: List all scenarios in a PhaseFolio project. Returns scenario IDs, names, created/updated timestamps, and top-line eNPV/rNPV. Use this to discover what scenarios exist before fetching o
  • Get Scenario: Fetch a PhaseFolio scenario's complete inputs (stage costs, durations, PoS, commercial assumptions, IRA settings) and computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, t

What data it sees

Do you need an account

No: the server works without sign-in

Biotech rNPV / probability-of-success engine for AI agents. Audit-grade asset valuation with signed dossier exports, cell-level evidence registers, and asset-anchored competitive landscape — the same engine healthcare investors and tech transfer offices use to value early-stage biotech assets, exposed directly to your AI analyst.

Tools

Public tier — no auth required

  • query_benchmarks — anonymized network statistics (PoS by indication × modality, cost / duration percentiles)
  • verify_export — verify a signed PhaseFolio dossier by content hash or URL; returns issued timestamp, methodology version, originating-org identifier
  • get_methodology — fetch any methodology section in citable form (backtest, PoS calibration, IRA framework, evidence standards, network benchmarks)

Bearer tier — request a token at app.phasefolio.com/contact

  • get_project — project metadata: indication, sub-indication, modality, biomarker, asset name, stage at entry
  • list_scenarios — scenarios in a project with top-line eNPV / rNPV
  • get_scenario — full scenario inputs + computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, top sensitivity drivers)
  • get_evidence — evidence-register entries: citations, sources, supporting documents, freshness
  • get_dossier — structured dossier JSON, mirroring the IC Dossier PDF / Excel exports
  • query_landscape — asset-anchored competitive landscape (comparable trials, competing programs, sponsor activity, biomarker overlap) sourced from CT.gov + FDA + curated enrichment

Trust artifacts

Every PhaseFolio dossier export carries a cryptographic signature tying file content to engine version and methodology version. AI agents can verify any artifact in one tool call. Public key at /.well-known/phasefolio-pubkey.pem.

Methodology is fully published and citation-ready at app.phasefolio.com/methodology. Backtested on a held-out cohort: 16 rheumatoid-arthritis programs, AUC 0.625, Wilson 95% CI on accuracy. Oncology backtest in progress.

Sources

Server tool list (9)

Raw names from tools/list. Only developers need these.

get_projectFetch a PhaseFolio project's metadata: indication, sub-indication, modality, biomarker, asset name, and stage at entry. Use this when you need to ground an analysis question in the project's clinical context before fetching scenarios.
list_scenariosList all scenarios in a PhaseFolio project. Returns scenario IDs, names, created/updated timestamps, and top-line eNPV/rNPV. Use this to discover what scenarios exist before fetching one in detail.
get_scenarioFetch a PhaseFolio scenario's complete inputs (stage costs, durations, PoS, commercial assumptions, IRA settings) and computed outputs (eNPV, rNPV, cumulative PoS, per-stage breakdown, top sensitivity drivers). This is the authoritative engine output — every signed export ties back to this payload.
get_evidenceFetch the evidence register entries for a scenario — the citations, sources, and supporting documents the analyst attached to back the assumptions. Use this when an analysis question references 'what's the evidence for X?'
get_dossierFetch the structured dossier JSON for a scenario — the same content rendered in the IC Dossier PDF/Excel exports, in machine-readable form. Includes verdict, drivers, assumptions, evidence summary, and (if available) signed-export hashes pointing to the latest signed artifacts.
query_landscapeFetch the asset-anchored competitive landscape for a project — comparable trials, competing programs, sponsor activity, and biomarker overlap. Sourced from CT.gov + FDA + PhaseFolio's curated enrichment. Use when an analysis question asks 'who else is working on this?' or 'what's the competitive context?'
query_benchmarksQuery PhaseFolio's network benchmarks — anonymized aggregate statistics across the network of scenarios (PoS by indication × modality, cost distributions, duration percentiles). L1 tier (no auth) returns lagged, low-granularity headlines; L3 tier (bearer auth) returns granular slices with biomarker stratification.
verify_exportVerify a signed PhaseFolio export. Accepts either a content hash (from a signed PDF/Excel) or a URL to a hosted artifact. Returns verification status (valid/tampered/unknown), issued timestamp, methodology version, and an anonymized originating-org identifier. Use this when a user shares a PhaseFolio dossier and you want to confirm it's authentic before citing the analysis.
get_methodologyFetch a PhaseFolio methodology section's full content (backtest, PoS calibration, IRA framework, evidence standards, network benchmarks, COGS benchmark, SG&A benchmark, tax benchmark). Designed for citation: each section has a stable URL and a methodology version identifier you can reference in analysis output.