Pharmaceutical Regulatory Intelligence
Comprehensive pharmaceutical regulatory intelligence MCP server.
What it can do
- Check Drug: Check a drug, medicine, active ingredient, or CAS number across pharmaceutical safety and regulatory datasets. Use when the user asks for DrugBank details, WHO Essential Medicines status,
- Check Drug Interactions: Check drug-drug interactions for one medication or a specific two-drug pair. Use when the user asks whether warfarin and aspirin interact, wants interaction severity, mechanis
- Check Adverse Events: Check FDA FAERS adverse-event records for a drug or active ingredient. Use when the user asks about reported side effects, serious outcomes, death reports, top reactions, age dis
What data it sees
Do you need an account
No: the server works without sign-in
Comprehensive pharmaceutical regulatory intelligence MCP server. 4 tools across 7 databases and 45,000+ records. Look up drugs across DrugBank (4,947 compounds), WHO Essential Medicines (782), Australian TGA (23,259 registered medicines), and FDA NDI notifications (1,330). Check drug-drug interactions (5,000 documented interactions) with severity grouping. Query FDA FAERS adverse event reports (2,000 top drugs). Full-text search across all pharmaceutical databases including ChEMBL bioactivity (7,941 records). Built by Two Halves — twohalves.ai
How to connect
How to connect Pharmaceutical Regulatory Intelligence to Claude
The server address to paste into Claude settings:
https://pharma-regulatory--twohalves.run.tools
- Open Claude (claude.ai or the desktop app).
- Go to Settings → Connectors.
- Click Add custom connector.
- Paste the server address copied below into Remote MCP server URL and click Add.
- In a chat, click + → Connectors and switch the new connector on.
Custom connectors are available on Free, Pro, Max, Team and Enterprise plans (Free is limited to one). On Team and Enterprise an organization Owner adds the connector first under Organization settings → Connectors.
Authorization
After you click Add, a sign-in window for the service opens. Sign in with your own account and approve access. Claude never sees your password.
How to connect Pharmaceutical Regulatory Intelligence to ChatGPT
The server address to paste into ChatGPT settings:
https://pharma-regulatory--twohalves.run.tools
- Open ChatGPT in a browser (chatgpt.com). A Plus, Pro, Business, Enterprise or Edu plan is required.
- Turn on developer mode once: Settings → Apps → Advanced settings → Developer mode.
- Open Settings → Connectors and click Create.
- Fill in the form: Name (anything), Description (one line about what the service does), MCP server URL (copy it below).
- Under Authentication choose OAuth if the service requires sign-in, otherwise None. Click Create.
- In a new chat open + → Apps/Connectors and enable the connector.
OpenAI has renamed this section before (Connectors → Apps/Plugins). If the label differs, search settings for "developer mode". On Business/Enterprise workspaces an admin must allow custom connectors first.
Authorization
On first use ChatGPT opens the service's sign-in window. Sign in and approve access.
How to connect Pharmaceutical Regulatory Intelligence to Cursor
The server address to paste into Cursor settings:
https://pharma-regulatory--twohalves.run.tools
Fastest: click Open in Cursor below and confirm the prompt.
Manually:
- In Cursor open Settings → Cursor Settings → MCP and click Add new global MCP server.
- Paste the JSON copied below into
~/.cursor/mcp.json(per project:.cursor/mcp.jsonin the repo root). - Save the file. The server appears in the MCP list; authorize it there if asked.
Authorization
If the service needs sign-in, an authorize button appears next to the server in the MCP list.
Server tool list (4)
Raw names from tools/list. Only developers need these.
| check_drug | Check a drug, medicine, active ingredient, or CAS number across pharmaceutical safety and regulatory datasets. Use when the user asks for DrugBank details, WHO Essential Medicines status, Australian TGA records, FDA NDI notifications, targets, dosage forms, indications, or regulatory lookup for a specific substance. Do not use for drug-drug interaction pair checks, FAERS adverse-event signal summaries, broad disease/topic discovery, or cosmetic/food/cannabis substances. The response includes identifiers, compound metadata, targets, schedules, dosage forms, indications, and regulatory records from matched datasets. |
| check_drug_interactions | Check drug-drug interactions for one medication or a specific two-drug pair. Use when the user asks whether warfarin and aspirin interact, wants interaction severity, mechanism, clinical effect, evidence, or management guidance for medication safety review. Do not use for general drug monographs, adverse-event frequency, regulatory status, or non-drug ingredient interactions. The response includes matching interaction pairs, severity, mechanism, clinical effect, evidence level, and management recommendations. |
| check_adverse_events | Check FDA FAERS adverse-event records for a drug or active ingredient. Use when the user asks about reported side effects, serious outcomes, death reports, top reactions, age distribution, or post-market safety signals for a medication. Do not use for interaction mechanisms, regulatory approval lookup, nutrition/supplement advice, or adverse events not tied to a drug name. The response includes report totals, serious outcome counts, death counts, top adverse reactions, and common patient age groups. |
| search_pharma | Search pharmaceutical regulatory and safety datasets by disease, drug class, endpoint, indication, or safety keyword. Use when the user needs broad discovery across DrugBank, WHO Essential Medicines, TGA ARTG, FAERS, FDA NDI, interactions, or ChEMBL before choosing a specific drug tool. Do not use for exact drug monographs, two-drug interaction checks, or FAERS summaries when the drug name is already known. The response includes cross-dataset matches with dataset labels, names, identifiers, snippets, and source-specific fields. |