BioCosm
Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.
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What it can do
What data it sees
Do you need an account
No: the server works without sign-in
Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.
Server tool list (13)
Raw names from tools/list. Only developers need these.
| search_nodes | Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation. |
| get_node | Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality. |
| get_writeup | Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score. |
| list_by_therapeutic_area | List all nodes in a given therapeutic area. |
| get_company_portfolio | Get a company's full drug/diagnostic portfolio from BioCosm. |
| get_stats | Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs. |
| get_staleness_report | Get writeup staleness report: overall stats, top stale nodes, data source freshness. |
| get_node_freshness | Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score. |
| find_by_target | Find all drugs that target a specific gene/protein. |
| find_by_phase | List drugs/diagnostics at a specific clinical phase. |
| find_related | Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs with the same mechanism_class |
| get_pos_score | Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored). |
| get_coverage | Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors. |