appendix

Appendix Appendix turns any AI health conversation into a board-certified physician's opinion — with a real prescription when clinically appropriate.

CommunityOnlineNo sign-inGlobalFreeCan modify data

What it can do

  • Search Knowledge Base: Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue
  • Submit Encounter: Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on com
  • List Conditions: List all conditions and medications available through Appendix

What data it sees

Do you need an account

No: the server works without sign-in

Appendix

Appendix turns any AI health conversation into a board-certified physician's opinion — with a real prescription when clinically appropriate. Your agent searches peer-reviewed medical literature, helps you write a structured clinical letter, and submits it through the Appendix API. A licensed physician personally reviews it and issues a prescription when appropriate, sent to the pharmacy of your choice.

The Knowledge Base is free and open to everyone. Clinical services (physician review + prescriptions) are a paid subscription available in supported US states — and you can start using the API with no signup required.

Install

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude.ai connectors

{ "mcpServers": { "appendix": { "url": "https://mcp.appendix.com/mcp" } } }

Tools

Tool Description
search_knowledge_base Search medical literature and treatment guidelines
submit_encounter Submit a clinical letter for board-certified physician review
list_conditions List available conditions and medications

Learn more at appendix.com.

How to connect

How to connect appendix to Claude

The server address to paste into Claude settings:

https://appendix--appendix.run.tools

  1. Open Claude (claude.ai or the desktop app).
  2. Go to Settings → Connectors.
  3. Click Add custom connector.
  4. Paste the server address copied below into Remote MCP server URL and click Add.
  5. In a chat, click + → Connectors and switch the new connector on.

Custom connectors are available on Free, Pro, Max, Team and Enterprise plans (Free is limited to one). On Team and Enterprise an organization Owner adds the connector first under Organization settings → Connectors.

Authorization

After you click Add, a sign-in window for the service opens. Sign in with your own account and approve access. Claude never sees your password.

How to connect appendix to ChatGPT

The server address to paste into ChatGPT settings:

https://appendix--appendix.run.tools

  1. Open ChatGPT in a browser (chatgpt.com). A Plus, Pro, Business, Enterprise or Edu plan is required.
  2. Turn on developer mode once: Settings → Apps → Advanced settings → Developer mode.
  3. Open Settings → Connectors and click Create.
  4. Fill in the form: Name (anything), Description (one line about what the service does), MCP server URL (copy it below).
  5. Under Authentication choose OAuth if the service requires sign-in, otherwise None. Click Create.
  6. In a new chat open + → Apps/Connectors and enable the connector.

OpenAI has renamed this section before (Connectors → Apps/Plugins). If the label differs, search settings for "developer mode". On Business/Enterprise workspaces an admin must allow custom connectors first.

Authorization

On first use ChatGPT opens the service's sign-in window. Sign in and approve access.

How to connect appendix to Cursor

The server address to paste into Cursor settings:

https://appendix--appendix.run.tools

Fastest: click Open in Cursor below and confirm the prompt.

Manually:

  1. In Cursor open Settings → Cursor Settings → MCP and click Add new global MCP server.
  2. Paste the JSON copied below into ~/.cursor/mcp.json (per project: .cursor/mcp.json in the repo root).
  3. Save the file. The server appears in the MCP list; authorize it there if asked.

Authorization

If the service needs sign-in, an authorize button appears next to the server in the MCP list.

Server tool list (3)

Raw names from tools/list. Only developers need these.

search_knowledge_baseSearch Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue
submit_encounterSubmit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally review the submission and provide clinical guidance and a prescription if appropriate.
list_conditionsList all conditions and medications available through Appendix